antidiabetic and hypolipidaemic activities of solenostemon monostachyus

Authors

jude e. okokon

louis u. amazu

lucky l. nwidu

abstract

background & aim: solenostemon monostachyus has remain invincible in ibibio ethnomedicine for the management of numerous ailment including diabetes mellitus. many of these ethnomedicinal claims are yet to be pharmacologically verified. the purpose of this study therefore was to subject the extract/fractions of solenostemon monostachyus used in folkloric management of diabetes to scientific assay. experimental: the crude extract and fractions of s. monostachyus (75 -225 mg/kg) were evaluated for antidiabetic activity in alloxan – induced diabetic rats. the antidiabetic activity during acute and prolong studies were investigated. glibenclamide, 10 mg/kg, was used as positive control. the blood glucose level (bgl) was measured by using a glucometer and the various lipids level were estimated using randox diagnostic kits. results & discussion: treatment of alloxan diabetic rats with the extract/fractions caused a significant (p

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Antidiabetic and hypolipidaemic activities of Solenostemon monostachyus

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Journal title:
journal of herbal drugs (an international journal on medicinal herbs)

Publisher: research center for medicinal plants & ethno-veterinary, i.a.u., shahrekord branch

ISSN 2008-8884

volume 6

issue 2 2015

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